abstract：BACKGROUND:Pemphigus herpetiformis (PH) is a rare subtype of pemphigus that presents challenges in diagnosis. OBJECTIVE:To review the presentation, diagnosis, and management of PH. METHODS:We reviewed the charts of all patients diagnosed and treated for PH in an immunobullous referral center between September 2007 an...

journal_title：International journal of dermatology

authors： Laws PM,Heelan K,Al-Mohammedi F,Walsh S,Shear NH

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Skin problems in the elderly population have rarely been the subject of scientific research. OBJECTIVES:The present study aimed to determine the prevalences of the most common dermatological conditions in elderly subjects and to investigate their associations with systemic diseases. METHODS:The study invol...

journal_title：International journal of dermatology

authors： Reszke R,Pełka D,Walasek A,Machaj Z,Reich A

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Huntington interacting protein 1 (HIP1), an antiapoptotic protein normally expressed in the brain, is highly expressed in Merkel cell carcinomas (MCCs). Given this, the aim of the current study was to ascertain the value of HIP1 as a histopathologic adjunct in the diagnosis of MCC. METHODS:In this retrospec...

journal_title：International journal of dermatology

authors： Marghalani S,Feller JK,Mahalingam M,Mirzabeigi M

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Female pattern hair loss (FPHL) is a common disorder but presents severe psychosocial problems in many female patients. Adipose tissue-derived stem cells (ADSCs) and conditioned media of ADSCs (ADSC-CM) are reported to promote hair growth in vitro. However, there are no clinical reports on the treatment of a...

journal_title：International journal of dermatology

authors： Shin H,Ryu HH,Kwon O,Park BS,Jo SJ

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Patterns of skin disease in developing nations are changing as frequencies of non-communicable diseases continue to increase. Appraisal of the current status of the disease profile is of utmost importance for health planning and resource allocation. METHODS:A prospective analysis of 895 cases of outpatient ...

journal_title：International journal of dermatology

authors： Akinboro AO,Mejiuni AD,Akinlade MO,Audu BM,Ayodele OE

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:Oral lichen planus (OLP) is a chronic inflammatory disease of unknown cause. Malignant transformation in OLP lesions may be favored by changes in the expression of proteins that regulate cell proliferation and apoptosis. This study aimed to investigate these issues by immunohistochemical staining for Bcl-2 a...

journal_title：International journal of dermatology

authors： Pigatti FM,Taveira LA,Soares CT

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Mortality rates in patients with bullous pemphigoid (BP) are higher than those in age-matched counterparts. However, the specific causes of death in BP subjects have not been evaluated systematically. OBJECTIVES:We sought to characterize the causes of death in patients with BP as recorded by death certifica...

journal_title：International journal of dermatology

authors： Barrick BJ,Lohse CM,Lehman JS

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Plantar hyperhidrosis is a common illness with significant impact on quality of life. Oxybutynin presents good short-term results, but longer follow-up results are lacking. We evaluated oxybutynin effectiveness in patients who were not surgically treated and who had at least six months of follow-up. METHODS...

journal_title：International journal of dermatology

authors： Wolosker N,Teivelis MP,Krutman M,de Paula RP,Kauffman P,de Campos JR,Puech-Leão P

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:CD4+ CD25+ T-regulatory (Treg) cells play critical roles in maintaining peripheral tolerance and preventing autoimmunity. As characteristics of Treg cells have not been precisely investigated in chronic urticaria (CU) yet, this study was performed. OBJECTIVE:To determine the frequencies of circulating CD4+ ...

journal_title：International journal of dermatology

authors： Arshi S,Babaie D,Nabavi M,Tebianian M,Ghalehbaghi B,Jalali F,Ahmadvand A,Gholami R

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Intralesional bleomycin is effective for the treatment of various dermatologic conditions. However, the efficacy of intralesional bleomycin for the treatment of corns has not been established. METHODS:A total of 50 patients with plantar corns were recruited and equally divided between groups A and B. Groups...

journal_title：International journal of dermatology

authors： Lee WJ,Lee SM,Won CH,Chang SE,Lee MW,Choi JH,Moon KC

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Psoriasis can significantly affect the physical, psychological, and social aspects of a patient's life. Many studies have evaluated the effects of psoriasis on quality of life (QoL), but results in many cases are contradictory. OBJECTIVES:This study was conducted to assess the relationships between the char...

journal_title：International journal of dermatology

authors： Fernández-Torres RM,Pita-Fernández S,Fonseca E

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Sunbathing on the beach is one of the main risks for skin cancer. OBJECTIVE:In the summer of 2010, a skin cancer prevention campaign aimed at beachgoers was undertaken on the western Costa del Sol (southern Spain). METHODS:The campaign took place on beaches during July and August. A multicomponent interven...

journal_title：International journal of dermatology

authors： de Troya-Martín M,Delgado-Sánchez N,Blázquez-Sánchez N,Ortega-Tudela G,Toribio-Montero JC,Jabalera-Mesa ML,Ríos-Almellones I,Rivas-Ruiz F

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Reduced cell-mediated immunity associated with pregnancy may cause a flaring or exacerbation of some skin conditions. Little is known about the magnitude of and risk factors for skin diseases among human immunodeficiency virus (HIV)-infected antiretroviral therapy-naïve pregnant women. METHODS:Cross-section...

journal_title：International journal of dermatology

authors： Shayo GA,Moshiro C,Spiegelman D,Mugusi FM,Chalamilla G,Msamanga G,Hawkins C,Fawzi W

更新日期：2014-10-01 00:00:00

abstract：:Certain cutaneous conditions have been reported to be associated with diabetes mellitus, insulin resistance, and metabolic syndrome. In this novel review paper, the evidence linking various cutaneous phenomena (e.g. skin tags, acanthosis nigricans, ear lobe creases, and xanthelasma) and metabolic syndrome and cardiova...

journal_title：International journal of dermatology

authors： Schilling WH,Crook MA

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Biologic therapies are more effective than conventional therapies in the treatment of psoriasis, but they are also more costly. OBJECTIVES:The aim of this study was to compare the cost-efficacy of etanercept, adalimumab, and ustekinumab therapies in the treatment of moderate to severe psoriasis in a Taiwane...

journal_title：International journal of dermatology

authors： Wang SH,Chi CC,Hu S

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Tranexamic acid (TA) is a traditional plasmin inhibitor, and its role in the renovation of damaged skin has become the topic of a lot of research. The aim of this study is to determine whether TA could repair the skin barrier by means of tight intercellular junctions. METHODS:Two kinds of damaged skin model...

journal_title：International journal of dermatology

authors： Yuan C,Wang XM,Yang LJ,Wu PL

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Though any drug can be a potential cause of such hypersensitivity reactions, paracetamol, an over-the-counter drug used extensively as an analgesic and antipyretic agent, is considered to be relatively safe, with hepatotoxicity as a major adverse effect only in large doses. MATERIALS AND METHODS:We report a...

journal_title：International journal of dermatology

authors： Biswal S,Sahoo SS

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Body piercing is a known and popular method of body ornamentation. Modern body piercing includes wearing jewelry in such body areas as the helix (ear), eyebrows, nose, lips, tongue, chin, nipples, navel, and genitals. The current piercing definition does not comprise piercing of the earlobe; however, this bo...

journal_title：International journal of dermatology

authors： Fijałkowska M,Kasielska A,Antoszewski B

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Melanoma is responsible for 75% of all skin cancer-related deaths. Lentigo maligna (LM), the most prevalent melanoma in situ (MIS), accounts for 79-83% of all MIS. Its location in the head and neck area requires that tissue be spared in the course of clearing the tumor. METHODS:We conducted a therapeutic st...

journal_title：International journal of dermatology

authors： Kassi K,Vanwijck R,Kanga JM

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Recently, the reactivation during treatment with tumor necrosis factor (TNF) blockers has exceptionally been described in patients with hepatitis B virus (HBV) antigen-negative (HBsAg). The objective was to evaluate the influence of anti-TNF agents in patients with psoriasis and serology suggesting past hepa...

journal_title：International journal of dermatology

authors： Navarro R,Concha-Garzón MJ,Castaño C,Casal C,Guiu A,Daudén E

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Pruritus is a common subjective symptom of psoriasis whose levels may be affected by a range of variables. The objective of this study was to evaluate the frequency of pruritus and its associations with clinical and psychological characteristics of psoriasis patients. MATERIALS AND METHODS:One-hundred and s...

journal_title：International journal of dermatology

authors： Janowski K,Steuden S,Bogaczewicz J

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Considerable studies showed that tumor suppressor phosphatase and tensin homolog (PTEN) deleted on chromosome 10 is a major tumor suppressor, which inhibits cell proliferation through inactivation of the PI3 kinase (PI3K)/Akt signal pathway. In many human tumors, there is loss of function or mutations in PTE...

journal_title：International journal of dermatology

authors： Li Y,Man X,You L,Xiang Q,Li H,Xu B,Chen Z,Zhang X,Lian S

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Chronic plaque psoriasis has a profound impact on a patient's daily life. To understand the effects of psoriasis treatments, it is essential to assess the patient's experience of symptoms and how they impact their daily life. The goal of this study was to develop and establish the content validity of a new p...

journal_title：International journal of dermatology

authors： Lebwohl M,Swensen AR,Nyirady J,Kim E,Gwaltney CJ,Strober BE

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Edema commonly accompanies surgical procedures and when excessive, can adversely affect surgical outcomes. The skin extracellular matrix, including one of its primary components, hyaluronan (HA), is a significant barrier to effective drainage of accumulated edematous fluid. Recombinant human hyaluronidase (r...

journal_title：International journal of dermatology

authors： Nekoroski T,Paladini RD,Sauder DN,Frost GI,Keller GA

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The aim of this study is to reveal demographic and clinical features of Behçet's disease (BD) in a Turkish population. METHODS:We retrospectively evaluated the clinical findings of 521 patients with BD. RESULTS:A total of 521 patients (287 female and 234 male) were included in this study. Onset signs: oral...

journal_title：International journal of dermatology

authors： Balta I,Akbay G,Kalkan G,Eksioglu M

更新日期：2014-05-01 00:00:00

abstract：:Eccrine poroma (EP) is a benign tumor of the eccrine duct. Multiple EPs are defined as eccrine poromatosis (EPS), an uncommon phenomenon. To date there are only eight reported cases of EPS. This review exemplifies the epidemiology, pathogenesis, differential diagnosis, and histology of EP, while reviewing the eight ca...

journal_title：International journal of dermatology

authors： Deckelbaum S,Touloei K,Shitabata PK,Sire DJ,Horowitz D

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Tuberous sclerosis is an autosomal dominant disorder with hamartomas in multiple organ systems. Facial angiofibromas (AF) are a common cutaneous manifestation of tuberous sclerosis. They may lead to significant cosmetic and psychological problems. Many treatment modalities have been used with variable satisf...

journal_title：International journal of dermatology

authors： Ma G,Wu P,Lin X,Chen H,Li W,Hu X,Jin Y

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Cutaneous melanoma is the most aggressive type of skin cancer, with high implications on the morbidity and mortality of patients. Matrix metalloproteinases (MMP) 2 and 9 have been involved in melanoma progression because they degrade important components of the basement membrane. We studied the relationship ...

journal_title：International journal of dermatology

authors： Candrea E,Senila S,Tatomir C,Cosgarea R

更新日期：2014-05-01 00:00:00

abstract：INTRODUCTION:Diffuse dermal angiomatosis is an entity in the spectrum of reactive angiomatoses characterized by erythematous plaques that mainly affect the lower extremities of patients with a personal history of peripheral vascular disease. Involvement of the breast is a rare event that has only been described as sing...

journal_title：International journal of dermatology

authors： Sanz-Motilva V,Martorell-Calatayud A,Rongioletti F,Escutia-Muñoz B,López-Gómez S,Rodríguez-Peralto JL,Vanaclocha F

更新日期：2014-04-01 00:00:00

abstract：:Psoriasis is a chronic inflammatory process associated with an increased risk of cardiovascular risk factors. sCD40L has been suggested to have a possible role in the pathogenesis, of psoriasis and is known to be associated with inflammation, atherogenesis and cardiovascular events. This study investigated cardiovascu...

journal_title：International journal of dermatology

authors： Erturan I,Köroğlu BK,Adiloğlu A,Ceyhan AM,Akkaya VB,Tamer N,Başak PY,Korkmaz S,Ersoy IH,Kilinç O

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Melanocytic nevi are well-known, important precursors of melanoma among children and adults. The adolescence period is an important period for nevi formation and evolution. This study provides data of a longitudinal study of nevi in a Hispanic adolescent population. MATERIALS AND METHODS:A cross-sectional s...

journal_title：International journal of dermatology

authors： Sosa-Seda IM,Valentín-Nogueras S,Figueroa LD,Sánchez JL,Mercado R

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Regulatory T cells (Tregs) play an important role in autoimmune diseases. In skin, the presence of Tregs is thought to be mandatory for suppression of autoreactive T cells. Here, we assess the number of Tregs in skin of healthy subjects and patients with an autoimmune dermatosis. METHODS:Immunohistochemical...

journal_title：International journal of dermatology

authors： Terras S,Gambichler T,Moritz RK,Altmeyer P,Lambert J

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Methotrexate (MTX) is a risky medication requiring careful attention to dosing and monitoring. Dosing and monitoring practices are not well characterized. AIMS:The aim of this study was to assess variation in the dosing and monitoring of methotrexate among Iranian dermatologists. METHODS:A questionnaire wa...

journal_title：International journal of dermatology

authors： Zargari O,Hejazi S,Shahidi-Dadras M,Younespour S,Robati R,Firooz A,Toosi P,Feldman SR

更新日期：2014-03-01 00:00:00

abstract：:In this article, we review the salient features of tinea versicolor and describe the epidemiology, clinical presentation, and histopathology of this mycosis in dark-skinned individuals. Tinea versicolor is caused by an overgrowth of the Malassezia genus. It manifests clinically as asymptomatic hypopigmented macules, h...

journal_title：International journal of dermatology

authors： Kallini JR,Riaz F,Khachemoune A

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:Whole-slide imaging with virtual microscopy is increasingly used as a tool in resident education and training, board certification and maintenance of certification examinations, and diagnostic evaluation. The objective of this study was to determine attitudes toward virtual microscopy compared with tradition...

journal_title：International journal of dermatology

authors： Brick KE,Comfere NI,Broeren MD,Gibson LE,Wieland CN

更新日期：2014-02-01 00:00:00

abstract：:The porphyrias are diverse in pathophysiology, clinical presentation, severity, and prognosis, presenting a diagnostic and therapeutic challenge. Although not easily curable, the dermatological manifestations of these diseases, photosensitivity and associated cutaneous pathology, can be effectively prevented and manag...

journal_title：International journal of dermatology

authors： Tintle S,Alikhan A,Horner ME,Hand JL,Davis DM

更新日期：2014-01-01 00:00:00

abstract：:Live bee acupuncture (Bong-Chim) dermatitis is an iatrogenic disease induced by so-called live bee acupuncture therapy, which applies the honeybee (Apis cerana) stinger directly into the lesion to treat various diseases in Korea. We present two cases of live bee acupuncture dermatitis and review previously published a...

journal_title：International journal of dermatology

authors： Park JS,Lee MJ,Chung KH,Ko DK,Chung H

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Mesenchymal neoplasms (sarcomas) of skin are rare. Patients with sarcomas were analyzed over the last decade. METHODS:Over a 10-year period, we conducted a retrospective analysis of patients diagnosed and treated in an urban academic teaching hospital in Saxony, Germany. Clinical and pathologic files were u...

journal_title：International journal of dermatology

authors： Wollina U,Koch A,Hansel G,Schönlebe J,Kittner T,Pabst F,Haroske G,Nowak A

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Pityriasis lichenoides (PL) is a self-limiting papulosquamous disease that may persist for years and is associated with a high relapse rate. To date, few comparative studies have investigated the efficacy of narrowband ultraviolet B (NB-UVB) phototherapy and other therapies in the treatment of PL. OBJECTIVE...

journal_title：International journal of dermatology

authors： Park JM,Jwa SW,Song M,Kim HS,Chin HW,Ko HC,Kim MB,Kim BS

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate possible associations of the five DNA polymorphic genotypes in the HLA region (transporter associated with antigen processing [TAP1; TAP1 333 a/b, TAP1 637 c/d], the HLA-DRB1*1501-rs3135388, tumor necrosis factor [TNF]α [-238 G/A] and NcoI TNFβ) with characteristics o...

journal_title：International journal of dermatology

authors： Vasku A,Bienertova-Vasku J,Izakovicova-Holla L,Pavkova Goldbergova M,Kozacikova Z,Splichal Z,Vasku V

更新日期：2013-08-01 00:00:00